The second edition of the DG’s Talk, hosted by IITA Director General and CGIAR Regional Director for Continental Africa, Dr Simeon Ehui, brought together a global audience for a timely and thought-provoking conversation on Africa’s development trajectory, anchored in agriculture, but extending far beyond it. At the center of the dialogue was Dr Brahima Sangafowa Coulibaly, whose global economic perspective helped frame the continent’s most pressing challenge: how to simultaneously drive food security, create jobs at scale, and achieve structural economic transformation.