This brief offers recommendations for key policy and investment priorities that are aimed at increasing the availability and supply of sufficient and affordable quality seed potatoes for internal use by EAC countries, with the surplus being traded to other EAC partner states. Such a strategy can ultimately boost yields and can unlock the potential of potatoes to contribute to multiple socioeconomic development goals. Results and recommendations focus on pragmatic options in three intervention areas: (1) policies, regulations, and markets; (2) infrastructure and technology investment; and (3) technical capacity development.