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CGIAR: Consultative Group on International Agricultural Research
Nourishing the Future through Scientific Excellence

Taking Stock of Biotech

At a biotechnology conference held recently in Guadalajara, Mexico, by the Food and Agriculture Organization (FAO) of the United Nations, disputes about genetically modified crops were notably absent, as a diverse group of participants - including CGIAR scientists - engaged in a timely and productive research-based dialogue about the wide range of biotechnologies now in use.

This is not to say that reservations about some biotechnologies were overlooked. In the opening plenary session, a small scale farmer from the Philippines took vigorous exception to the idea of researchers "targeting biotechnologies to the poor," as a conference document put it, and argued for active farmer involvement in research. Participants also heard the voice of civil society on issues such as the concentration of transgenic crops in the hands of multinational companies and the possible dangers of introducing these materials in centers of crop genetic diversity, like Mexico.

Yet, hardened ideological positions on such issues did not define the dynamic of the conference deliberations. Rather, participants systematically took stock of a wide range of recent experiences with biotechnology in developing countries, drawing lessons from past successes and failures, and they looked to the future, underlining challenges and examining options for dealing with these effectively.

A good time and place to re-examine biotechnology

Both the timing and location of the conference, which brought together about 300 participants from 68 countries, were significant. Organized against a background of deteriorating global food security and of rising concern about the negative impacts of climate change on developing country agriculture, the conference recognized a growing consensus that investment in research needs to be renewed and that increased agricultural productivity must be at the heart of any strategy for reducing hunger and poverty.


Photo: IRRI.

With respect to the location, it is important to recall that Mexico was among the first countries to witness mass demonstrations against rising food prices in 2008. In response to major challenges and opportunities for its agriculture, Mexico has built a significant biotechnology capacity - which Mariano Ruiz-Funes Macedo, undersecretary of agriculture, speaking in the opening session, said consists of about 1,000 scientists working in 100 laboratories.

Mexico thus provided a particularly good vantage point from which to re-examine the role of biotechnology in confronting agriculture's multiple crises and the level of

investment this work merits - issues that were implicit in the conference organizers' call for a decisive move "beyond business-as-usual" in agricultural research for development.

A broad overview of biotechnology in developing countries

To inform the conference discussions, FAO prepared a set of detailed background papers, including one each on five key sectors: crops, forests, livestock, fisheries and aquaculture, and food processing and food safety. These documents, featuring instructive case studies, gauge the current status of biotechnologies in developing countries and explore possible applications.

A sixth document deals with policy issues - such as the need for orienting biotechnologies to the needs of the poor - that are involved in strengthening national capacity to make informed decisions about the use of biotechnologies in food and agriculture. The delegations of FAO member states as well as representatives of national, international and civil society organizations offered a rich collection of comments on key aspects of these issues - including the farmers' role in research, gender equity, public participation in key decisions, intellectual property rights, biosafety and biotechnology training and education.

A seventh document draws lessons learned from the experience of developing countries, outlines options available to them and presents a lengthy set of action priorities, with a sharp focus on building national capacities. (See the web link below for access to all conference documents.)

One inescapable overall conclusion, said FAO assistant director-general Modibo Traoré, is that, while there are many cases of successful application of biotechnologies in developing countries, they have so far been used much more to address the needs of farmers in the developed world - a situation he insisted must change.

Reflecting national realities

One striking feature of the conference was its wide scope, covering diverse sectors and starting from a wide definition of biotechnology, taken from the Convention on Biological Diversity.

An article in the Mexican media insinuated that the broad definition of biotechnology was merely a subterfuge for keeping transgenic crops under the radar, so to speak. But the organizers insisted that, on the contrary, they were merely reflecting the reality of developing country experience, which ranges from the use of so-called traditional biotechnologies, such as tissue culture and artificial insemination, to the use of more sophisticated techniques, like molecular markers and the controversial option of genetic modification.

The important point, according to Shivaji Pandey, director of FAO's Plant Production and Protection Division, is for countries to have comprehensive strategies, policies and regulatory frameworks, which neither stifle technical innovation nor treat biotechnologies as a panacea but rather ensure that decisions about them are well-informed and remain a national prerogative.

CGIAR scientists weigh in

Several CGIAR researchers contributed to the discussions.

The main reason international centers use biotechnologies is that these tools are essential in unlocking the potential of genetic resources for purposes such as crop improvement, said Thomas Lumpkin, director general of the International Maize and Wheat Improvement Center (CIMMYT), who delivered a plenary presentation on behalf of the Alliance of CGIAR Centers.

Center scientists have already employed molecular genomic techniques to characterize numerous samples of many crop species, explained Dave Hoisington, deputy director general-research at the International Crops Research Institute (ICRISAT), and they are now considering plans to sequence the genomes of entire germplasm collections. In facilitating a session on genetic resources, he referred to them as "the building blocks of global food security."

Those comments echoed a central point of the keynote message by M.S. Swaminathan, chair of the M.S. Swaminathan Research Foundation. He suggested that, just as biodiversity has served as the basic raw material for efforts so far to achieve sustainable food security, it can also provide the feedstock for biotechnologies designed to help make agriculture more climate resilient.

For both purposes, researchers have generated an impressive array of genomic resources in recent years, including various types of molecular markers. Overviews of such work were presented and discussed in a parallel session facilitated by Rajeev Varshney, who has a joint appointment with ICRISAT and the CGIAR's Generation Challenge Program (GCP). Genomic resources are particularly abundant now for cereal crops, though good progress is being made as well with grain legumes, animals and tree crops. Such resources are so plentiful, in fact, that they constitute a kind of "information tsunami," as one presenter put it, which presents researchers with major challenges in bioinformatics and data management.

Putting genomic resources to work through a variety of strategies referred to collectively as molecular breeding was the subject of a parallel session facilitated by Jean-Marcel Ribaut, director of the GCP, which is hosted by CIMMYT. CGIAR Centers have registered important successes with such strategies, including the development of pearl millet varieties with resistance to downy mildew and rice varieties tolerant to flooding.

The session called attention to various support services and networks now available for developing country scientists, including the Molecular Breeding Platform recently launched by the GCP, which will provide breeders in developing countries with better access to tools for modern breeding. The session also examined factors and prospects for success with molecular breeding, which vary greatly among developing countries. A key challenge for each country is to carefully weigh the cost-effectiveness of molecular breeding, compared with conventional approaches, a task that is still less than straightforward.

As Lumpkin stressed, the CGIAR Centers offer developing countries valuable assistance in meeting such challenges through collaborative research on a wide array of biotechnologies, conducted increasingly through innovative public-private partnerships, backed by an unwavering commitment to strengthening national research capacities.

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