Africa Oldest Enemy
In June, the International Livestock Research Institute (ILRI),
the Doyle Foundation, and a Host-Pathogen Consortium funded by the
Wellcome Trust sponsored a four-day workshop on People, Mice
and Livestock, the Story of Trypanosomosis in Africa. The
disease kills people and cattle across a swath of sub-Saharan
Africa as large as the continental United States.
Medical as well as veterinary experts from diverse
disciplines-from cell, molecular, parasite and vector biology to
genetics, immunology and vaccinology to biochemistry,
bioinformatics and proteomics-shared their latest research
findings, explored synergies and identified research gaps in an
effort to combat trypanosomosis. Young technicians and scientists
were among the participants.
Deo Mdumu Birungi, a graduate fellow from the Ugandan Ministry
of Agriculture studying for a PhD in animal breeding and genetics
at ILRI, described the meeting as "a fantastic opportunity. We
don't normally get to participate in such workshops with well
established international scientists."
For over 30 years, ILRI has been in the forefront of the battle
to better control trypanosomosis, an "orphan" tropical
disease of livestock and their keepers. "The disease is as
important as the parasite is biologically fascinating," said
John Donelson, Distinguished Professor of Biochemistry and
Investigator at the Howard Hughes Medical Institute at the
University of Iowa.
Terry Pearson, Professor of Biochemistry and
Microbiology at the University of Victoria, describing the heroic
attempts of scientists to find ways to control this disease and its
tsetse vector over the past century, said, "No continent
remains dominated by one livestock disease to the extent that
Africa is by trypanosomosis."
African animal trypanosomosis costs the continent up to $5
billion a year while the number of new cases of the human form of
the disease is estimated to be 300,000 people, most of whom will
die untreated. The toll on Africa's economy is also
significant. In an article in Nature magazine in 1991,
John Brady argued that "The tsetse fly and the trypanosome
parasites it carries have kept Africa from undergoing the
agro-economic revolution that occurred in the Middle East around
4000 B.C."
ILRI will be facilitating similar meetings as host of the Hub of
the Biosciences Eastern and Central Africa Network, which is
supported by the New Partnership for Africa's Development
(NEPAD). The Doyle Foundation, ILRI and a Host-Pathogen Consortium
funded by the Wellcome Trust cosponsored the African Trypanosomosis
Workship. The Doyle Foundation and ILRI produced DVDs of the
meeting, which are being sent to participants as well as other
stakeholders.
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